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关键词： 农药化学   药物研发   材料化学   亲脂性   有机氟化学   铜催化   生物电子等排体  

摘要： 二氟甲基(HCF2)具有较强亲脂性和吸电子效应,可作为氢键供体,又能充当羟基和巯基的生物电子等排体[1],因而在药物研发、农药化学和材料化学等领域中受到广泛关注;如何向分子中引入二氟甲基成为有机氟化学的研究热点.二氟甲基化是一种直接而有效的策略,目前已发展出了许多二氟甲基化试剂以及二氟甲基化方法[2].然而,不对称二氟甲基化少有研究,仍具有较大的挑战性.

关键词： Pyrene  

摘要： Molecules that experience a change in their fluorescence emission due to the effect of fluorescence enhancement upon binding events, like chemical reactions or a change in their immediate environment, are regarded as fluorescent probes, because of their high selectivity and advantages in the fields of chemical, biological, and medical chemistry. Fluorescent probes have become a predominant aid for the detection of target materials like metal cations, anions, and neutral molecules in the bio-imaging field and also have great importance in the detection of reactive oxygen species (ROS) and reactive carbonyl species (RCS) in living cells, air, soil, and food. Pyrene and its derivatives are important polycyclic aromatic hydrocarbons that act as fluorophores and are widely used as a fluorescent probe on account of their strong emission of fluorescence in live cells, very low cytotoxicity, high fluorescence quantum yield, easy modification, and outstanding cell permeability. In this review, the methods of design and synthesis of versatile pyrene fluorophores for the selective and sensitive quantification of their activity will inspire further reaction development in this interesting area.

关键词： 针对性教育   产业发展模式   分子化学   智能制造   材料化学   人工智能   化学原理   综合性化工  

摘要： "新工科建设"是基于全球范围内产业革新升级和经济发展模式转变所提出的针对性教育方针。以化学原理、分子化学、材料化学等为代表的重点且热门的化工课程,在化工产业发展模式发生转变之际,迫切需要创新改革教学理念、调整课程教学模式,将新工科建设对化工专业教学的改革要求具体落实。在新工科建设教育目标引领下,高校化工专业要积极贯彻"实践型、应用型"人才培养方略,坚持探索化工专业实践教学的优化路径,根据学校和专业教学实际,探索建立"产学研"协同同进的化工专业教学模式。以互联网信息技术为手段,以当前与化工生产与化工科研相关的云计算、人工智能、大数据、智能制造等方面的应用能力为培养方向。大力强化对学生工程实践能力的培养,将新时期的化工人才塑造成科研创新力强、工程实践水平高的综合性化工人才。

关键词： 虚拟仿真   材料化学实验   双万计划  

摘要： 根据材料化学实验及学科发展的新特点和新规律,切实开展对材料结构表征的系列虚拟仿真实验教学的探索和改革,通过对课程内容及学生综合能力评估体系的合理设计,充分开拓学生思路,深化学生对材料化学研究的认识,培养学生的分析问题能力、逻辑思维能力,加强对材料化学所学知识的巩固,激发学习材料化学前沿科研课题的积极性,提高院校办学水平和人才培养质量,促进材料化学专业国家级一流本科“双万”专业建设和发展。

关键词： Machine learning   Catalysis   Materials Chemsitry  

摘要： The development of advanced materials is an important aspect of modern life. However, the discovery of novel materials involves searching the vast chemical space to find materials with desired properties. Recent developments in the applications of Machine Learning (ML) in materials chemistry show promise to accelerate the material discovery process. In this perspective article, we highlight the importance of ML in materials chemistry. We discuss few examples of ML applications in synthesis, characterization, and predicting activities of materials. Finally, we discuss the challenges in this field and how the progress in ML in chemistry is leveraged together with advanced robotics to perform automated optimization of material discovery.

关键词： 应用型高校   人才培养,就业  

摘要： 根据中部地区材料化学类人才需求,依据河南城建学院特色,本文根据对企业调研及毕业生跟踪调研数据,结合应用型本科高校人才培养模式的现有问题及改进方法,在人才培养目标,课程体系建设,教学组织及方法,职业生涯规划方面开展改革和实践,探索以就业为导向的本科院校的应用型人才培养模式,提高毕业生的就业竞争力,解决就业问题。

关键词： 纳米金属氧化物   化学收缩   水泥净浆  

摘要： 为明确部分常见纳米氧化物对水泥基材料化学收缩的影响,采用TiO_(2)、Fe_(3)O_(4)、Fe_(2)O_(3)、CuO、ZnO为实验对象,等质量代替水泥,采用ASTM化学收缩实验测试方法,研究上述纳米材料对水泥基材料化学收缩变化的影响。实验结果表明:5种纳米材料掺水泥基材料化学收缩均经历三阶段,分别为急速变化区,缓慢变化区,平稳区。且因各纳米材料的影响作用不同,水泥基材料进入阶段的时间也不同。5种纳米材料的最优掺量对水泥基材料化学收缩的改善作用大小为:TiO_(2)>Fe_(3)O_(4)>Fe_(2)O_(3)>CuO>ZnO。

关键词： General Public   High School/Introductory Chemistry   First-Year Undergraduate/General   Second-Year Undergraduate   Upper-Division Undergraduate   Laboratory Instruction   Organic Chemistry   Hands-On Learning/Manipulatives   Conductivity   Polymerization  

摘要： Writing instruments, such as pens, are ubiquitous in the classroom, but their functionality is largely for one purpose: they are used to represent ideas and record information on paper. However, by replacing the conventional ink in a pen with easy-to-synthesize conducting polymer-based inks, it is possible to change a simple writing utensil into a materials processing tool that can create circuits, sensors, and potentially other optoelectronic devices. The Polysketch pen is a modified ballpoint pen that contains a conductive polyaniline ink that can be synthesized safely by high school and undergraduate students in a 1-3 hour laboratory setting. The synthesis and formulation of the ink and the construction of the pen expose students to nanomaterial synthesis, chemical/material purification, and functional design with a specific goal: producing an appropriately viscous, fast-drying ink with a suitable loading level of polyaniline for conductive properties. The Polysketch pen leaves conductive traces on paper, which can be used to draw simple circuits or construct sensors responding to mechanical strains or ambient chemical species. This activity has the objective of introducing materials-relevant polymer synthesis into high school and undergraduate laboratories while introducing concepts in conductive polymers such as doping/dedoping and percolation in conductive networks. The activity is constructed such that students have the opportunity to explore processing-structure-properties-performance relationships by optimizing ink formulation. Most importantly, students will ultimately arrive at a tangible, versatile product and tool that enables them to explore other types of interactive devices and art to "trace a line of their creation".

关键词： 人才培养模式   “双一流”建设   材料化学专业  

摘要： 文章以南昌航空大学材料化学专业为例,从立足立德树人,加强课程思政建设;聚焦“两性一度”,提升学生创新创业能力;瞄准信息前沿,强化课程资源与教材建设;注重培养和引进,建设“双师型”教学团队四个方面探索了“双一流”建设背景下高校人才培养模式改革。

关键词： 思政教育   参与式教学   材料化学专业   课程教学改革  

摘要： 以甘肃农业大学材料化学专业《材料化学进展(双语)》课为例,对思政教育与专业课同向同行、协同共进的建设内容进行探讨.利用课程改革平台,针对材料化学专业特点,将思想政治教育、参与式教学与知识传授有机融合,创新教学载体和教学方式,着力提升教学效果,为实现中华民族伟大复兴培养合格人才.